Gigantism: Excess Growth Hormone

Cause of the disease

Gigantism is a disorder that occurs when the pituitary gland, the secretion gland, overproduces growth hormone (GH). It is a disordered growth condition, mainly in the arms and legs, accompanied by corresponding growth in height.


It can also occur in childhood, before the calcification process is completed, or during puberty, when genetic failures prevent normal calcification of this phase. In both cases, there is an overproduction of growth hormone, thus occurring the picture of gigantism.


Acromegaly is a disorder related to gigantism, which occurs due to excessive production of growth hormone already in adulthood (phase in which the growth cartilages are already closed). In this case, excessive growth occurs in the hands, feet and chin.